Are you trying to use read_var or write_var? You'll need topological addressing enabled in the target PLC so you can read / write standard modbus holding registers or coils.
You need to elaborate on what is not working. Does your code compile? Are you getting an error being returned? The example in the help file is not too bad for these instructions.
Upload a screenshot of your code, or zip the STU file if it's not very big so we can see what you've done so far.