Using a purchased version of RLinx, you can use DDE to do this from an event in excel.
If you are already reding values using the Copy and Paste DDE Link feature, then your are 90% done.
You will have to detemine the event(s) in terms of Excel, in which you want to send a DDE update to the PLC.
You will have to edit a VBA routine for the event you choose.
In the code you will open a DDE channel, write the value, and, at some point in the excel application, you will close the channel.
There is an oversimplified example in RSLinx Help, search for topic "Excel".
There is a fantastic example at MrPLC.com
Paul