It depends on what you want data you need from HART.
The presence of HART assumes a conventional 4-20mA analog signal.
If all you need is flow rate, you use a PLC analog input, connect the 4-20mA transmitter output and you get flow rate.
HART also provides secondary, 3rd and 4th variables, and status and diagnostic data as digital data superimposed on the 4-20mA signal.
The FX300 has total flow as secondary, temp or line pressure as 3rd or 4th (if the line pressure option is part of the meter)
Whether any particular PLC has an I/O card that can grab HART data is specific to the brand. I believe A-B CLX has a HART I/O module, but I'm foggy on details. Other brands might, too.
The most common method of grabbing the secondary, 3rd and 4th variables as analog values is Moore Industries's breakout box, the DIN rail mounted HIM module. It takes the 4-20mA from the transmitter, outputs up to 2 or 3 variables.
http://www.miinet.com/products/sg_hart.shtml
Moore also has a HART to Modbus converter.
There are USB HART modems that programs like Siemens' Windows based PDM uses to communicate with transmitter, primarily for configuration purposes, but I'm not aware of its use otherwise.
Pepperl & Fuchs and Phoenix Contact offer HART multiplexors that deal with multiple HART field devices. The hardware is costly and it assumes a software package can deal with the data on the demultiplexed side. I am only aware of US paper companies using this for valve positioner diagnostic maintenance management, so there doesn't seem to be much discussion of it.