Which output is giving you trouble?
The only one I see an issue with is O:0/0. It's being used in several different rungs.
All controlled by the same bit B3/0. Is the HMI writing to B3/0?.
It may be writing to it continuously and the software is to slow to respond. Try disconnecting the HMI and then toggle the bit manually.
The PLC is connected to 4 HMI's. O:0/0 is an air valve that can be triggered by any of the HMI's.
But I'm having troubles with all of the outputs. When live the inputs light up but the outputs do not.