Basically, the "Service" mode starts and runs RSLinx each time your computer is started, even if there are no nodes connected. This can create some problems, if RSLinx ties up communications ports that are needed by other equipment.
The regular mode allows you to start and stop RSLinx as needed.
Select DDE > Options or View > Options to display the Options dialog box which contains the General, DDE, and Services tabs.
"Services" gives the option of starting RSLinx Services each time your system is started.