Wonderware won't create the tags from the CLX database if that is what you are asking. You can however export/import. I've found that it is much quicker to create your Wonderware tags first. Build your HMI application and assign your tagnames appropriately (Discrete, Integer, Real). Use the checkbox that says use item name from tag name. Then, when you are finished, do a DBDump of the WW tag database into a CSV file. Go into CLX and create one type of each tag and do an export of the CLX tag database into another CSV file (this will show you the format CLX is expecting). Compare the two and cut/paste the appropriate cells from the WW CSV into the CLX CSV, import it back into CLX and you now have all your I/O tags in CLX that you defined in WW.
You can of course go the opposite direction if you feel your CLX program is more defined. It depends on the process whether it is more HMI centric or PLC. The only caveat is that WW has a limitation (I think 21 characters) on tagnames so be sure to keep your CLX tagnames less than the restriction.
As for your device groups, these correspond to the access names you create in WW. Normally, you create a device group for each interval of update that you need. If it is a smallish application, then 1 device group at 1000ms is sufficient. You don't need to fill in the tag info. Then in WW, you'll have an accessname with a topic of the same group name, and the application will be DASABCIP.