On a mechanical vacuum gauge, the bourdon tube is referenced to the atmosphere surrounding the bourdon tube.
To measure gauge pressure vacuum with a DP transmitter, like one would with a mechanical vacuum gauge on the manifold of car engine, connect the high side to the vacuum port and leave the low side of the DP open to atmosphere, because atmospheric pressure is the reference for gauge pressure measurements.
When you screw a plug into the low side on a DP transmitter, you are compressing the volume of air behind the plug, creating a false reference point.
-10kPa is only 3 inches of mercury (Hg), which is only 10% vacuum from atmosphere. That's a pretty 'light' vacuum. Are you sure you have enough range to measure the vacuum level needed?
If this is 4-20mA, 4.0mA will be -10kPa, 0kPa (atmosphere) will be 12.0mA, 10kPa will be 20.0mA