I use multiple outputs in a rung all the time. For example, an alarm routine may contain a latch, acknowledge bit, Diff up to re-trigger a strobe, output for a SCADA system (grouped to improve read times), a flashing output for a light and then used in conjunction with a series of bit count instructions to control other functions etc.
I get really annoyed when a PLC will only allow multiple outputs that do no have separate bits in the output lines. If a routine is fully enclosed in one rung, it is easier for others to follow. If you have to break it up into multiple rungs, it is a pain in the "A" as it is more difficult to have to go to a series of rungs using internal bits. It also takes up more memory and increases scan times.
beerchug