The red X is both bad news and good news.
The bad news is that it means that RSLinx can't communicate with the controller at all. It's a timeout.
The good news is that this means there's probably nothing wrong with RSLinx or the EDS files !
If you can connect to the CompactLogix over RS-232 and bridge through to the Ethernet daughtercard, verify the IP address, the subnet mask, and the default gateway. Post those along with the IP address of your PC, and its subnet mask, and its default gateway, and we'll have a discussion about IP subnetting.
There's always something new to learn; I spent today working on a 20-bit subnet (instead of the usual 24-bit) but my browser won't see anything that's not on the same 24-bit mask as my PC. Weird.