Notice that there is noting in the field at the top of your photo for "Current Application:"
This tells me that you need to go into the menus and find the place where you choose the application to run on power up. Somewhere in the menus is also a place to tell the unit what to do on power which can be set to go to this configuration page or to simple run the selected application.
It has been a few years since I dealt with the PanelView Plus so I can't be much more specific. I used to have to support a plant with many of these in service. I had to write up instructions for the maintenance techs to follow when replacing a failed HMI. The instructions were a full page of steps to be able to copy the application to internal storage from a memory card, set the application to run, and set the power up options to run the application. Before I wrote the instructions, the techs would frequently fumble around and figure out how to run the application from external storage. Then hey'd remove the memory card and walk away thinking all was well.
A few hours later, the machine would be power cycled and the Panelview would either boot up to the config screen or go looking for external storage which was no longer present and they would get called back to the machine to do it all again.
We did see occasionally a problem occur where the internal storage of a faulty HMI would be wiped out and we would have to reload it from external storage. This might be similar to your condition as well. You say you can still select the application from internal storage, but yout picture seems to indicate that there is no application available for selection.